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UniGel-65Heparin Heparin Affinity Chromatography Resin

UniGel is a monodisperse spherical porous cross-linked polyacrylate "hard gel" chromatography resin with hydrophilic surface modification, offering excellent pressure resistance, hydrophilicity, and biocompatibility. Protein A affinity resins and ion exchange resins based on this matrix have been widely used in biopharmaceutical purification. UniGel-65Heparin is a heparin affinity resin developed on the UniGel matrix, featuring a special extended arm and bonding technology to couple high-purity heparin sodium ligand. It provides high binding capacity and selectivity with low ligand leakage and minimal non-specific adsorption, primarily used for affinity chromatography purification of antithrombin III, coagulation factors, lipoproteins, esterases, hormones, and interferons.


Performance Specifications

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Product ModelUniGel-65Heparin
Separation PrincipleHeparin affinity
MatrixPolymethacrylate
Particle Size65 μm
Dynamic Binding Capacity*~ 5 mg·mL-1 (Antithrombin III) 
Maximum Pressure 0.8 MPa
CIP2 M NaCl
Recommended Flow Rate100 - 500 cm/h
pH Stability4-12
Chemical StabilityStable in common aqueous buffers (0.05 M sodium acetate, 8 M urea, 6 M guanidine hydrochloride, non-ionic detergents, 10% glycerol)
Operating Temperature2-40 ℃
Storage20% ethanol, 4 - 25 ℃



Ordering Information

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ProductPackage SizeCatalog #
UniGel-65Heparin30 mL17012-065100-2030
50 mL17012-065100-2050
100 mL17012-065100-2100
300 mL17012-065100-2300
500 mL17012-065100-2500
1 L17012-065100-1001
5 L17012-065100-1005
10 L17012-065100-1010
50 L17012-065100-1050
100 L17012-065100-1100


Note: Pre-packed columns of 7.7 mm × 22 mm, 16 mm × 25 mm, and 7.7 mm × 100 mm are available. For additional specifications or custom requirements, please contact us.