Microspheres for In Vitro Diagnostics (IVD)

Latex-enhanced turbidimetry utilizes microspheres surface-modified with specific ligands that bind specifically to the analyte through immunologic recognition, triggering an agglutination reaction of the microspheres, and achieves precise quantification by detecting changes in scattered light intensity. Immunochromatography uses microspheres as signal labels: red/blue microspheres generate visual signals and can be directly used for rapid qualitative screening, or europium (Eu) fluorescent microspheres can be used for high-sensitivity quantitative analysis.

The magnetic microparticle-based chemiluminescence immunoassay (CLIA) integrates three key technologies: magnetic separation, chemiluminescence, and immunoassay. Using 1–3 μm magnetic beads with high suspension stability and a large specific surface area as separation carriers, it is perfectly compatible with fully automated instruments based on magnetic separation technology, enabling rapid, automated detection with high sensitivity and high specificity.

The ME series magnetic extraction beads combine the advantage of two technology platforms: solid-phase extraction and magnetic separation, maintaining the ability of solid-phase extraction technology to efficiently extract and enrich target substances from mixtures of multiple complex components, while taking full advantage of magnetic material separation technology's suitability for automated, high-throughput sample pre-treatment processes.

In fully automated protein purification, magnetic beads dramatically improve both ease of use and result reproducibility. For IP and Co-IP, we recommend MP3 (3.0 μm) magnetic beads: their balanced particle size delivers optimal suspension properties and a fast magnetic response, while the non-porous surface effectively suppresses non-specific binding. For small-scale, high-throughput purification like antibody display, the MA series magnetic beads provide clear advantages—their hydrogel backbone offers exceptional porosity and protein binding capacity, perfectly meeting the need for efficient capture from limited sample volumes.

Nucleic acid extraction and purification is the most fundamental and critical sample preparation step in molecular diagnostics and genetic testing. We offer a comprehensive range of magnetic beads, with core products covering nucleic acid extraction, specific hybridization capture, and NGS library preparation size-selection beads, empowering efficient sample preparation with outstanding quality.

Flow cytometry microspheres are high-quality microspheres prepared specifically for applications in flow cytometry, such as absolute counting, instrument quality control, and the development of multiplex assay reagents. This product series features a highly uniform particle size distribution.

As critical reference materials for instrument calibration, method validation and quality control, standard particles play an essential role in high-precision measurements across scientific research, industrial applications and quality assurance. We provide traceable standard particles with highly uniform particle sizes and excellent sphericity, covering a size range of 0.10–200 μm. These particles fully satisfy the calibration and quality control requirements of all types of particle sizing instruments.