NanoGel-50SP HP Ion Exchange Chromatography Resin
NanoGel-50SP HP is based on polystyrene/divinylbenzene (PS-DVB) microspheres with excellent mechanical strength, good chemical stability, uniform particle size, and an open supermacroporous structure. Surface hydrophilic modification reduces non-specific adsorption, and unique surface functionalization technology delivers high binding capacity, high alkali resistance, high flow rate, high resolution, and low back pressure. Our solution is designed to meet the separation and purification needs of biomacromolecules such as monoclonal antibodies (mAb), viruses/vaccines, and high-molecular-weight recombinant proteins.
Performance Specifications
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| Product Model | NanoGel-50SP HP |
| Separation Principle | Strong cation exchange |
| Matrix | Polystyrene/divinylbenzene |
| Particle Size | 50 μm |
| Ligand | -CH2CH2CH2SO3— |
| Ligand Density | ~0.14 meq·mL-1 |
| Dynamic Binding Capacity | ~70 mg/mL (hIgG) |
| Maximum Pressure | 2.0 MPa |
| CIP | 1 M NaOH |
| Recommended Flow Rate | 300-1200 cm/h |
| pH Stability | 1~14 |
| Chemical Stability | Compatible with all commonly used buffers, 1 M acetic acid, 1 M sodium hydroxide, 1 M hydrochloric acid, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine hydrochloride, 8 M urea, and other common organic solvents; avoid strong oxidizing agents. Do not expose to strong oxidizing agents (e.g., hypochlorite), oxidizing acids (e.g., nitric acid), strong reducing agents (e.g., sulfite), acetone, or benzyl alcohol. |
| Operating Temperature | 4-30 ℃ |
Ordering Information
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| Product | Package Size | Catalog # |
| NanoGel-50SP HP | 30 mL | 04062-050150-2030 |
| 50 mL | 04062-050150-2050 | |
| 100 mL | 04062-050150-2100 | |
| 300 mL | 04062-050150-2300 | |
| 500 mL | 04062-050150-2500 | |
| 1 L | 04062-050150-1001 | |
| 5 L | 04062-050150-1005 | |
| 10 L | 04062-050150-1010 | |
| 50 L | 04062-050150-1050 | |
| 100 L | 04062-050150-1100 |
Note: Pre-packed columns of 7.7 mm × 22 mm, 16 mm × 25 mm, and 7.7 mm × 100 mm are available. For additional specifications or custom requirements, please contact us.