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PureMax 50SP Ion Exchange Chromatography Resin

The matrix is made of polystyrene/divinylbenzene (PS-DVB), ensuring excellent mechanical strength and chemical stability. The macroporous structure facilitates rapid diffusion and efficient separation of large biomolecules, laying a solid foundation for efficient purification processes. Advanced surface hydrophilic modification effectively reduces non-specific adsorption, improving the recovery and purity of target biomolecules and further enhancing production efficiency. Unique surface functionalization technology endows the resin with high binding capacity, high alkali resistance, high flow rate, high resolution, and low back pressure. Combined with optimized chromatography performance, the high binding capacity of PureMax 50SP significantly reduces operating and time costs while maintaining efficient separation, delivering substantial economic benefits for biopharmaceutical manufacturers.


Performance Specifications

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Product ModelPureMax 50SP
Separation PrincipleStrong cation exchange
MatrixPolystyrene/divinylbenzene
Particle Size55 μm
Ligand-CH2CH2CH2SO3-
Ligand Density~0.12 meq·mL-1
Dynamic Binding Capacity~100 mg/mL (hIgG)
Maximum Pressure 2.0 MPa
CIP0.5 - 1 M NaOH
Recommended Flow Rate300-1200 cm/h
pH Stability1~14
Chemical StabilityCompatible with all commonly used buffers, 1 M acetic acid, 1 M sodium hydroxide, 1 M hydrochloric acid, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine hydrochloride, 8 M urea, and other common organic solvents; avoid strong oxidizing agents.
Do not expose to strong oxidizing agents (e.g., hypochlorites), oxidizing acids (e.g., nitric acid), strong reducing agents (e.g., sulfites), acetone, or benzyl alcohol.


Ordering Information

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ProductPackage SizeCatalog #
PureMax 50SP30 mL04112-050100-2030
50 mL04112-050100-2050
100 mL04112-050100-2100
300 mL04112-050100-2300
500 mL04112-050100-2500
1 L04112-050100-1001
5 L04112-050100-1005
10 L04112-050100-1010
50 L04112-050100-1050
100 L04112-050100-1100


Note: Pre-packed columns of 7.7 mm × 22 mm, 16 mm × 25 mm, and 7.7 mm × 100 mm are available. For additional specifications or custom requirements, please contact us.