UniSP-30S Strong Cation Exchange Chromatography Resin
NanoMicro UniSP-30S strong cation exchange chromatography resin features a polymer matrix that has been surface-modified with hydrophilic groups and then bonded with ion exchange groups. This design provides excellent biocompatibility and physicochemical stability for bioactive molecules, significantly improving purification efficiency. It is ideally suited for the purification of small biomolecules such as small proteins, peptides, nucleic acids, and antibiotics.
UniSP-30S utilizes hydrophilic membrane surface modification, offering low non-specific binding, high resolution with small pore sizes, and high loading capacity for small molecules. The specific performance parameters are shown in the table below:
Performance Specifications
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| Product Model | UniSP-30S |
| Separation Principle | Strong cation exchange |
| Matrix | Polymethacrylate (PMMA) |
| Particle Size | 36 μm |
| Ligand | -(CH2)3SO3- |
| Ligand Density | ~0.23 meq·mL-1 |
| Dynamic Binding Capacity | ~60 mg·mL-1 (Lysozyme) |
| Maximum Pressure | 1.0 MPa |
| CIP | 0.5 M NaOH |
| Recommended Flow Rate | 50-300 cm/h |
| pH Stability | 2~12 |
| Chemical Stability | All commonly used buffers, 1 M acetic acid, 1 M sodium hydroxide, 1 M hydrochloric acid, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine hydrochloride, 8 M urea and other common organic solvents; avoid contact with strong oxidizing agents. |
| Operating Temperature | 4-30 ℃ |
| Storage Conditions | 20% ethanol, 4-25℃ |
Ordering Information
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| Product | Package Size | Catalog # |
| UniSP-30S | 30 mL | 04022-030050-2030 |
| 50 mL | 04022-030050-2050 | |
| 100 mL | 04022-030050-2100 | |
| 300 mL | 04022-030050-2300 | |
| 500 mL | 04022-030050-2500 | |
| 1 L | 04022-030050-1001 | |
| 5 L | 04022-030050-1005 | |
| 10 L | 04022-030050-1010 | |
| 50 L | 04022-030050-1050 | |
| 100 L | 04022-030050-1100 |
Note: NanoMicro offers a wide range of preparative pre-packed columns, including 7.7*22mm (NmTRAP 1mL), 16*25mm (NmTRAP 5mL), 7.7*100mm (NmSCREEN 4.7mL), 16*100mm (NmPREP 20mL), 26*100mm (NmPREP 50mL), as well as NmVALID and NmLOAD series preparative pre-packed columns with inner diameters of 8/11/16/26/50mm and adjustable bed heights, and NmPILOT