UniSP-50XS Strong Cation Exchange Chromatography Resin
NanoMicro UniSP-50XS strong cation exchange chromatography resin features a polymer matrix that has been surface-modified with hydrophilic groups before coupling ion exchange ligands, providing excellent biocompatibility and physicochemical stability for biomolecules while significantly improving purification efficiency. It is ideally suited for the purification of small biomolecules such as small proteins, peptides, nucleic acids, and antibiotics.
UniSP-50XS utilizes hydrophilic surface modification, offering low non-specific binding, high resolution with small pore sizes, and high loading capacity for small molecules. Key performance specifications are listed below:
Performance Specifications
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| Product Model | UniSP-50XS |
| Separation Principle | Strong cation exchange |
| Matrix | Polymethacrylate (PMMA) |
| Particle Size | 55 μm |
| Ligand | -(CH2)3SO3- |
| Ligand Density | ~0.25 meq·mL-1 |
| Dynamic Binding Capacity | ~55 mg·mL-1 (Lysozyme) |
| Maximum Pressure | 0.8 MPa |
| CIP Cleaning-in-Place | 0.5 M NaOH |
| Recommended Flow Rate | 100-500 cm/h |
| pH Stability | 2~12 |
| Chemical Stability | Compatible with all commonly used buffers, 1 M acetic acid, 1 M sodium hydroxide, 1 M hydrochloric acid, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine hydrochloride, 8 M urea and other common organic solvents; avoid contact with strong oxidizing agents. |
| Operating Temperature | 4-30 ℃ |
| Storage Conditions | 20% ethanol, 4-25℃ |
Ordering Information
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| Product | Package Size | Catalog # |
| UniSP-50XS | 30 mL | 04022-050030-2030 |
| 50 mL | 04022-050030-2050 | |
| 100 mL | 04022-050030-2100 | |
| 300 mL | 04022-050030-2300 | |
| 500 mL | 04022-050030-2500 | |
| 1 L | 04022-050030-1001 | |
| 5 L | 04022-050030-1005 | |
| 10 L | 04022-050030-1010 | |
| 50 L | 04022-050030-1050 | |
| 100 L | 04022-050030-1100 |
Note: NanoMicro offers a wide range of preparative pre-packed columns, including 7.7*22mm (NmTRAP 1mL), 16*25mm (NmTRAP 5mL), 7.7*100mm (NmSCREEN 4.7mL), 16*100mm (NmPREP 20mL), 26*100mm (NmPREP 50mL), as well as NmVALID and NmLOAD series preparative pre-packed columns with inner diameters of 8/11/16/26/50mm and adjustable bed heights, and NmPILOT