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UniDEAE-50XS Weak Anion Exchange Chromatography Resin

NanoMicro UniDEAE-50XS weak anion exchange chromatography resin features a polymer matrix that has been surface-modified with hydrophilic groups before coupling with ion exchange ligands. This design provides excellent biocompatibility and physicochemical stability for bioactive macromolecules, significantly improving purification efficiency. It is ideally suited for the purification of small biomolecules such as small proteins, peptides, nucleic acids, and antibiotics.

UniDEAE-50XS utilizes hydrophilic surface modification, offering low non-specific adsorption, high resolution for small molecules, and high binding capacity. Key technical specifications are listed below:


Performance Specifications

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Product ModelUniDEAE-50XS
Separation PrincipleWeak anion exchange
MatrixPolymethacrylate (PMMA)
Particle Size55 μm
Ligand-CH2CH2N(CH2CH3)2
Ligand Density~0.20 meq·mL-1
Maximum Pressure0.8 MPa
CIP (Clean-in-Place)0.5 M NaOH
Recommended Flow Rate100-500 cm/h
pH Stability2~12
Chemical StabilityCompatible with all common buffers, 1 M acetic acid, 1 M NaOH, 1 M HCl, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine-HCl, 8 M urea, and other common organic solvents; avoid strong oxidizing agents.
Operating Temperature4-30 ℃
Storage Conditions20% ethanol, 4-25 ℃


Ordering Information

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ProductPackage SizeCatalog #
UniDEAE-50XS30 mL04023-050030-2030
50 mL04023-050030-2050
100 mL04023-050030-2100
300 mL04023-050030-2300
500 mL04023-050030-2500
1 L04023-050030-1001
5 L04023-050030-1005
10 L04023-050030-1010
50 L04023-050030-1050
100 L04023-050030-1100


Note: NanoMicro offers a wide range of preparative pre-packed columns, including 7.7*22mm (NmTRAP 1mL), 16*25mm (NmTRAP 5mL), 7.7*100mm (NmSCREEN 4.7mL), 16*100mm (NmPREP 20mL), 26*100mm (NmPREP 50mL), as well as NmVALID and NmLOAD series preparative columns with adjustable bed heights (inner diameters of 8/11/16/26/50mm), and NmPILOT series pilot-