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UniGel-65Q HC Ion Exchange Chromatography Resin

To improve production efficiency and reduce costs in large-scale biopharmaceutical manufacturing, particularly for the separation and purification of biomacromolecules such as antibodies (mAb), viruses, vaccines, and high-molecular-weight recombinant proteins, NanoMicro has developed a new generation of high-performance ion exchange resin, UniGel-65Q HC. This product offers high binding capacity, high alkali resistance, high flow rate, high resolution, and low back pressure.

Advantages of UniGel-65Q HC Ion Exchange Resin:

  • Monodisperse PMMA microspheres: enable higher flow rates and taller bed heights

  • Excellent hydrophilicity: low non-specific binding

  • Outstanding chemical and pH stability: extends service life

  • Excellent reproducibility: superior batch-to-batch consistency


Performance Specifications

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Product ModelUniGel-65Q HC
Separation PrincipleStrong anion exchange
MatrixPolymethacrylate (PMMA)
Particle Size~65μm
Ligand—CH2N+( CH3)3
Ligand Density~0.24 meq·mL-1
Dynamic Binding Capacity~140 mg·mL-1 (BSA)
Maximum Pressure 0.5 MPa
CIP0.5 M NaOH
Recommended Flow Rate150-750 cm/h
pH Stability2~12
Chemical StabilityAll commonly used buffers, 1 M acetic acid, 1 M sodium hydroxide, 1 M hydrochloric acid, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine hydrochloride, 8 M urea and other common organic solvents; avoid contact with strong oxidizing agents.
Operating Temperature4-30 ℃



Ordering Information

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ProductPackage SizeCatalog #
UniGel-65Q HC30 mL04084-065100-2030
50 mL04084-065100-2050
100 mL04084-065100-2100
300 mL04084-065100-2300
500 mL04084-065100-2500
1 L04084-065100-1001
5 L04084-065100-1005
10 L04084-065100-1010
50 L04084-065100-1050
100 L04084-065100-1100



Note: Pre-packed columns of 7.7 mm × 22 mm, 16 mm × 25 mm, and 7.7 mm × 100 mm are available. For additional specifications or custom requirements, please contact us.