We highly value your personal privacy. When you visit our website, please consent to the use of all cookies. For more information on personal data processing, please visit the Privacy Policy


Select a Country or Region

UniGel-65SP HC Ion Exchange Chromatography Resin

Ion Exchange Chromatography (IEX) separates biomolecules based on differences in their surface charge (type, number, and distribution). NanoMicro offers a comprehensive range of IEX resins based on both monodisperse and polydisperse polymer microspheres. These resins feature hydrophilic surface modification followed by bonding of ion exchange groups, and are available in multiple series to meet the demands of capture, intermediate purification, polishing, and analytical purification. With excellent biomolecule compatibility and bed stability, our solutions support bioprocessing from laboratory to industrial scale.

Key advantages of UniGel-65SP HC:

1) Macroporous PMMA matrix with high rigidity, ideal for scale-up;

2) Optimized ligand with enhanced salt tolerance;

3) Unique surface hydrophilization process minimizes non-specific binding;

1) Low compression and swelling factors (significantly lower than agarose and dextran gels) ensure high bed stability;

2) High-strength matrix enables faster flow rates and taller beds, improving purification efficiency;

3) Superior alkali resistance extends resin lifetime, increases productivity, reduces production costs, and enhances operational efficiency.


Performance Specifications

Swipe Left
Product ModelUniGel-65SP HC
Separation PrincipleStrong cation exchange
MatrixPolymethacrylate (PMMA)
Particle Size~ 65 μm
Ligand—(CH2)3SO3-
Dynamic Binding Capacity~115 mg/mL (IgG)
Ionic Capacity0.13 meq·mL-1
Max Operating Pressure 0.5 MPa
CIP0.5 M NaOH
Recommended Flow Rate150-750 cm/h
pH Stability2~12
Chemical StabilityCompatible with all common buffers, 1 M acetic acid, 1 M NaOH, 1 M HCl, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine HCl, 8 M urea, and other common organic solvents; avoid strong oxidizing agents.


Ordering Information

Swipe Left
ProductPackage SizeCatalog #
UniGel-65SP HC30 mL04082-165100-2030
50 mL04082-165100-2050
100 mL04082-165100-2100
300 mL04082-165100-2300
500 mL04082-165100-2500
1 L04082-165100-1001
5 L04082-165100-1005
10 L04082-165100-1010
50 L04082-165100-1050
100 L04082-165100-1100


Note: Pre-packed columns are available in 7.7 mm × 22 mm, 16 mm × 25 mm, and 7.7 mm × 100 mm formats. For additional sizes or custom requirements, please contact us.