NW Rose Plus HAM HP Multimodal Chromatography Media
NW Rose Plus HAM HP is a multimodal chromatography medium designed for anion exchange and hydrophobic interaction. It utilizes a next-generation agarose backbone with optimized agarose concentration and crosslinking, enabling better pore size control and enhanced mechanical strength. This significantly improves pressure resistance and flow properties.
Key features of the NW Rose Plus HAM HP series include:
High dynamic binding capacity and excellent pressure-flow characteristics
Enhanced chemical and physical stability for easy scale-up
High batch-to-batch reproducibility
Simple CIP and sanitization procedures
Suitable for both laboratory and industrial scale applications
Performance Specifications
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| Product Model | NW Rose Plus HAM HP |
| Separation Principle | Multimodal Anion Exchange |
| Matrix | High-flow, high-rigidity agarose microspheres |
| Ligand | Anion + Phenyl |
| Dynamic Binding Capacity | 45-85 mg·mL-1 |
| (mAb, residence time 4-5 min, ~pH 8) | |
| Ionic Capacity | 80-120 μmol·mL-1(Cl-) |
| Maximum Pressure | 0.3 MPa |
| CIP | 0.5 M NaOH |
| Recommended Flow Rate | 60-300 cm/h |
| (50/30 column, bed height 10 cm) | |
| Maximum Flow Rate | 600 cm/h (0.1 MPa, XK26/30 column, bed height 15 cm, 25℃) |
| pH Stability | 2-12 (working), 2-14 (CIP) |
| Chemical Stability | Common aqueous solutions, 1 M NaOH, 6 M guanidine HCl, 30% isopropanol, 70% ethanol |
| Operating Temperature | 4-40℃ |
| Storage Conditions | 20% ethanol, 4-30 ℃ |
Ordering Information
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| Product | Package Size | Catalog # |
| NW Rose Plus HAM HP | 25 mL | 60053-371500-2025 |
| 100 mL | 60053-371500-2100 | |
| 500 mL | 60053-371500-2500 | |
| 1 L | 60053-371500-1001 | |
| 5 L | 60053-371500-1005 | |
| 10 L | 60053-371500-1010 |
Note: Pre-packed columns are available in 7.7 mm × 22 mm, 16 mm × 25 mm, and 7.7 mm × 100 mm formats. For additional specifications or custom requirements, please contact us.