NW Rose Plus HCM Multimodal Chromatography Resin
NW Rose Plus HCM is a weak cation-exchange, hydrophobic multimodal chromatography resin. Built on a highly cross-linked, rigid agarose microsphere matrix, this series features optimized agarose concentration, cross-linking chemistry, and cross-linking cycles for better pore size control and enhanced bead rigidity, significantly improving pressure tolerance and flow performance.
Key features of NW Rose Plus HCM multimodal resin:
High dynamic binding capacity at high conductivity
Excellent flow properties
Enhanced chemical and physical stability for easy scale-up
Simple CIP and sanitization
Suitable for both laboratory and industrial scale-up
Performance Specifications
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| Separation Principle | Multimodal cation exchange |
| Matrix | High-flow, high-rigidity agarose microspheres |
| Particle Size | 75 μm |
| Dynamic Binding Capacity | ＞40 mg/mL |
| Maximum Pressure | 0.3 MPa |
| CIP | 0.5 M NaOH |
| Recommended Flow Rate | 60-300 cm/h (50/30 column, 10 cm bed height) |
| Maximum Flow Rate | 600 cm/h (0.1 MPa, XK26/30 column, 15 cm bed height, 25℃) |
| pH Stability | 2-12 (working), 2-14 (CIP) |
| Chemical Stability | Common aqueous solutions, 6 M guanidine hydrochloride, 30% isopropanol, 70% ethanol |
| Operating Temperature | 4-40℃ |
| Storage Conditions | 20% ethanol, 4-30 ℃ |
Ordering Information
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| Product | Package Size | Catalog # |
| NW Rose Plus HCM | 25 mL | 60053-531700-2025 |
| 100 mL | 60053-531700-2100 | |
| 500 mL | 60053-531700-2500 | |
| 1 L | 60053-531700-1001 | |
| 5 L | 60053-531700-1005 | |
| 10 L | 60053-531700-1010 |
Note: Pre-packed columns are available in 7.7 mm × 22 mm, 16 mm × 25 mm, and 7.7 mm × 100 mm formats. For additional specifications or custom requirements, please contact us.