NW Rose Plus HCM HP Multimodal Chromatography Media
NW Rose Plus HCM HP is a weak cation-exchange, hydrophobic multimodal chromatography resin. Built on a highly cross-linked, high-rigidity agarose microsphere matrix, this series achieves better pore size control and enhanced rigidity through optimized agarose concentration, cross-linking chemistry, and cross-linking cycles, significantly improving pressure tolerance and flow performance.
Key features of the NW Rose Plus HCM HP series include:
High dynamic binding capacity and high resolution at high conductivity
Excellent pressure-flow characteristics
Enhanced chemical and physical stability for easy scale-up
Simple CIP and sanitization procedures
Suitable for both laboratory and industrial scale applications
Performance Specifications
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| Separation Principle | Multimodal cation-exchange |
| Matrix | High-flow, high-rigidity agarose microspheres |
| Particle Size | 50 μm |
| Dynamic Binding Capacity | >58mg/ml hIgG |
| Ionic Capacity | 70-120 μmol/mL |
| Maximum Pressure | 0.3 MPa |
| CIP | 0.5 M NaOH |
| Recommended Flow Rate | 60-300 cm/h (50/30 column, bed height 10 cm) |
| Maximum Flow Rate | 600 cm/h (0.1 MPa, XK26/30 column, bed height 15 cm, 25℃) |
| pH Stability | 2-12 (working), 2-14 (CIP) |
| Chemical Stability | Common aqueous solutions, 1 M NaOH, 6 M guanidine hydrochloride, 30% isopropanol, 70% ethanol |
| Operating Temperature | 4-40℃ |
| Storage Conditions | 20% ethanol, 4-30 ℃ |
Ordering Information
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| Product | Package Size | Catalog # |
| NW Rose Plus HCM HP | 25 mL | 60053-371600-2025 |
| 100 mL | 60053-371600-2100 | |
| 500 mL | 60053-371600-2500 | |
| 1 L | 60053-371600-1001 | |
| 5 L | 60053-371600-1005 | |
| 10 L | 60053-371600-1010 |
Note: Pre-packed columns are available in 7.7 mm × 22 mm, 16 mm × 25 mm, and 7.7 mm × 100 mm formats. For additional sizes or custom requirements, please contact us.