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UniMSP-30XS Multimodal Chromatography Resin

NanoMicro UniMSP-30XS multimodal chromatography resin features a polymer matrix with a hydrophilic surface modification and bonded ion-exchange groups, providing excellent biocompatibility and physicochemical stability for biomolecules. This significantly enhances purification efficiency, making it ideal for the purification of small biomolecules such as small proteins, peptides, nucleic acids, and antibiotics.

UniMSP-30XS utilizes a hydrophilic surface layer modification that delivers low non-specific binding, high resolution for small molecules, and high loading capacity. Key performance specifications are listed below:


Performance Specifications

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Product ModelUniMSP-30XS
Separation PrincipleMultimodal Ion Exchange
MatrixPolymethacrylate (PMMA)
Particle Size33 μm
Ligand-(CH2)3SO3-
Ligand Density~0.25 meq·mL-1
Dynamic Binding Capacity~80 mg·mL-1 (Lysozyme)
Maximum Pressure1.0 MPa
CIP0.5 M NaOH
Recommended Flow Rate50-300 cm/h
pH Stability2~12
Chemical StabilityCompatible with all common buffers, 1 M acetic acid, 1 M NaOH, 1 M HCl, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine-HCl, 8 M urea, and other common organic solvents. Avoid strong oxidizing agents.
Operating Temperature4~30 ℃
Storage Conditions20% ethanol, 4~25℃


Ordering Information

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ProductPackage SizeCatalog #
UniMSP-30XS30 mL04012-030030-2030
50 mL04012-030030-2050
100 mL04012-030030-2100
300 mL04012-030030-2300
500 mL04012-030030-2500
1 L04012-030030-1001
5 L04012-030030-1005
10 L04012-030030-1010
50 L04012-030030-1050
100 L04012-030030-1100


Note: NanoMicro offers a wide range of preparative pre-packed columns, including 7.7*22mm (NmTRAP 1mL), 16*25mm (NmTRAP 5mL), 7.7*100mm (NmSCREEN 4.7mL), 16*100mm (NmPREP 20mL), 26*100mm (NmPREP 50mL), as well as NmVALID and NmLOAD series preparative columns with inner diameters of 8/11/16/26/50mm and adjustable bed heights, and NmPILOT series pilo