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UniMSP-50XS Multimodal Chromatography Resin

NanoMicro UniMSP-50XS multimodal chromatography resin features a polymer matrix that is surface-modified with hydrophilic groups and then bonded with ion-exchange ligands, offering excellent biocompatibility and physicochemical stability for biomolecules. This significantly enhances purification efficiency. It is ideally suited for the purification of small biomolecules such as small proteins, peptides, nucleic acids, and antibiotics.

UniMSP-50XS utilizes hydrophilic surface modification, providing low non-specific binding, high resolution for small molecules, and high loading capacity. Key performance specifications are listed below:


Performance Specifications

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Product ModelUniMSP-50XS
Separation PrincipleMultimodal Ion Exchange
MatrixPolymethacrylate (PMMA)
Particle Size52 μm
Ligand-(CH2)3SO3-
Ligand Density~0.20 meq·mL-1
Dynamic Binding Capacity~65 mg·mL-1 (Lysozyme)
Maximum Pressure0.8 MPa
CIP0.5 M NaOH
Recommended Flow Rate100-500 cm/h
pH Stability2~12
Chemical StabilityCompatible with all commonly used buffers, 1 M acetic acid, 1 M sodium hydroxide, 1 M hydrochloric acid, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine hydrochloride, 8 M urea, and other common organic solvents; avoid contact with strong oxidizing agents.
Operating Temperature4~30 ℃
Storage Conditions20% ethanol, 4~25℃



Ordering Information

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ProductPackage SizeCatalog #
Uni®MSP-50XS30 mL04012-050030-2030
50 mL04012-050030-2050
100 mL04012-050030-2100
300 mL04012-050030-2300
500 mL04012-050030-2500
1 L04012-050030-1001
5 L04012-050030-1005
10 L04012-050030-1010
50 L04012-050030-1050
100 L04012-050030-1100



Note: NanoMicro offers a wide range of preparative pre-packed columns, including 7.7*22mm (NmTRAP 1mL), 16*25mm (NmTRAP 5mL), 7.7*100mm (NmSCREEN 4.7mL), 16*100mm (NmPREP 20mL), 26*100mm (NmPREP 50mL), as well as NmVALID and NmLOAD series preparative pre-packed columns with adjustable bed heights (inner diameters of 8/11/16/26/50mm), and NmPILOT se