UniPS 30-100 Reversed Phase Polymer Chromatography Resin

NanoMicro offers monodisperse reversed phase polymer chromatography resins in various particle sizes and pore sizes. Based on matrix and characteristics, they are available in five series: UniPS^®, Uni^®PMM, Uni^®PSN, Uni^®PSA, and NM. These resins are primarily used for laboratory analysis and purification of organic compounds, natural products, proteins, insulin, peptides, and nucleic acids. With excellent alkaline resistance, long service life, and minimal peak tailing for basic compounds, they complement reversed phase silica media in separation performance and solvent compatibility.

Figure 1. Chemical structure of UniPS^®

UniPS^®30-100 monodisperse reversed phase polymer resin is based on highly cross-linked polystyrene/divinylbenzene (PS/DVB) (Figure 1). The abundant phenyl groups in the matrix provide high hydrophobicity and strong reversed phase retention, enabling unique surface modifications and rich selectivity. The high cross-linking density delivers excellent mechanical strength and chemical stability, allowing medium-to-high pressure DAC packing and resistance to extreme acidic or alkaline pH and mixed organic solvent regeneration.

Compared to similar products on the market, UniPS^®30-100 offers the following advantages:

• Narrower particle size distribution: CV≤3%;

• High mechanical strength: highly cross-linked PS/DVB matrix for superior pressure resistance; withstands repeated high-pressure DAC packing without breakage;

• Long service life: corrosion-resistant, contamination-resistant, easy to regenerate, and cost-effective;

• Excellent chemical stability: suitable for purification across pH 1-14.