UniPSN 30-300 Reversed Phase Polymer Chromatography Resin

NanoMicro offers monodisperse reversed phase polymer chromatography resins in various particle sizes and pore sizes. Based on different matrices and characteristics, they are available in UniPSN and UniPSA series. These resins are primarily used for separation and purification of organic compounds, natural products, proteins, insulin, peptides, and nucleic acids. With excellent alkaline resistance, long service life, and minimal peak tailing for basic compounds, they complement reversed phase silica resins in separation performance and solvent compatibility.

UniPSA series monodisperse reversed phase polymer resins use highly cross-linked polystyrene/divinylbenzene (PS/DVB) as the matrix, while UniPSN series monodisperse reversed phase polymer resins use polystyrene/divinylbenzene/polyvinylpyrrolidone (PS/DVB/PVP) as the matrix. The abundant phenyl groups in the matrix provide high hydrophobicity and relatively strong reversed phase retention. The highly cross-linked matrix offers high mechanical strength and excellent chemical stability, enabling resistance to high pressure, suitability for medium/high-pressure DAC packing, and tolerance to extreme acidic or alkaline pH and mixed organic solvent regeneration.

Compared to similar products on the market, UniPSN and UniPSA series offer the following advantages:

• Narrower particle size distribution: CV≤3%;

• High mechanical strength: highly cross-linked PS/DVB, PS/DVB/PVP matrix, more pressure-resistant, repeated high-pressure DAC packing without breakage;

• Long service life: corrosion-resistant, contamination-resistant, easy regeneration, low operating cost;

• Excellent chemical stability: suitable for separation and purification at pH 1-14