UniHybrid 8-120 C18 Hybrid Silica Chromatography Resin
The UniHybrid® series chromatography resins are based on high-purity monodisperse porous silica microspheres produced by NanoMicro's patented technology. A dense surface hybridization is applied to the particle and pore structure surfaces, introducing an organic-inorganic hybrid layer containing methylene bridge structures onto the silica surface, followed by bonding and end-capping. This unique surface hybridization technology significantly enhances the chemical stability of the resin, providing acid and alkaline pH tolerance similar to polymer-based resins, while combining the mechanical strength of high-purity silica resins with the chemical stability of polymer resins, along with their respective excellent performance in chromatographic purification. Additionally, the surface chemical treatment alters the silanol density and increases organic carbon content, imparting unique separation selectivity to the hybrid silica.
Compared to similar products on the market, UniHybrid® 8-120 C18 offers the following unique advantages:
Monodisperse silica resin with extremely narrow particle size distribution, CV ≤ 5%;
Precisely controlled pore size and distribution, effective specific surface area, and pore volume for high loading capacity;
Uniform particle size, surface modification, and pore design deliver high column efficiency and excellent separation performance;
Excellent chemical stability, suitable for purification across pH 1-11.
Performance Specifications
Separation Principle | Reversed Phase Chromatography |
Matrix | Monodisperse Silica |
Particle Size | 8 µm |
Pore Size | 120 Å |
Particle Size CV | ≤5% |
Pressure Limit | ＜600 bar |
Pore Volume | ~1.00 cm3/g |
Specific Surface Area | ~350 m2/g |
Bulk density | ~0.60 g /mL |
Carbon Content | ≥16% |
pH Range | 1~11 |
Ordering Information
Product | Package Size | Catalog # |
UniHybrid® 8-120 C18 | 30 g, 50 g, 100 g, 300 g, 500 g, 1 kg, 5 kg, 10 kg, 50 kg, 100 kg | 19501-080012 |