UniHybrid 8-200 C8 Hybrid Silica Chromatography Resin

UniHybrid^® series chromatography resins are based on high-purity monodisperse porous silica microspheres manufactured using NanoMicro's proprietary technology. A dense surface hybridization is applied to the particle and pore structure surfaces, introducing an organic-inorganic hybrid layer containing methylene bridge structures onto the silica surface, followed by bonding and end-capping. This unique surface hybridization technology significantly enhances the chemical stability of the resin, providing acid and alkaline pH tolerance similar to polymer-based resins. As a result, it combines the mechanical strength of high-purity silica resins with the chemical stability of polymer resins, along with the excellent performance derived from both in chromatographic purification. Additionally, the surface chemistry modification alters the silanol density and increases the organic carbon content, imparting unique separation selectivity to the hybrid silica.

Compared to similar products on the market, UniHybrid^® 8-200 C8 offers the following unique advantages:

• Monodisperse silica resin with extremely narrow particle size distribution, CV ≤ 5%;

• Precisely controlled pore size and distribution, effective specific surface area, and pore volume for high loading capacity;

• Uniform particle size, surface modification, and pore design deliver high column efficiency and excellent separation and purification performance;

• Excellent chemical stability, suitable for separation and purification at pH 1-11.