UniSil 10-100 C8 Reversed-Phase Silica Chromatography Resin
UniSil® 10-100 C8 is a key member of NanoMicro's UniSil® product line. This reversed-phase chromatography resin features a surface-modified UniSil® silica matrix with bonded reversed-phase groups, offering uniform particle size, high mechanical strength, high column efficiency, and high resolution. Its pore structure and chemical bonding are particularly well-suited for the separation and purification of small molecules such as antibiotics, peptides, and natural products.

UniSil® 10-100 C8 Chemical Structure
UniSil® 10-100 C8 utilizes advanced surface bonding and end-capping technologies, providing excellent chemical stability. After 5 years of storage at room temperature, re-testing of multiple batches shows no significant changes in QC results compared to the initial QC analysis.
Compared to similar products on the market, UniSil®10-100 C8 offers the following unique advantages:
• Monodisperse silica resin with extremely narrow particle size distribution, CV ≤ 5%;
• Precisely controlled pore size and distribution, effective specific surface area, and pore volume for high loading capacity;
• Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application needs;
• Excellent chemical stability, suitable for separation and purification at pH 2-8.
Performance Specifications
| Separation Principle | Reversed-Phase Chromatography |
| Matrix | Monodisperse Silica |
| Particle Size | 10 µm |
| Pore Size | 100 Å |
| Particle Size CV | ≤5% |
| Pressure Limit | <600 bar |
| Pore Volume | ~1.00 cm3/g |
| Specific Surface Area | ~450 m2/g |
| Bulk density | ~0.55 g /mL |
| Carbon Content | ~11 % |
| pH Range | 2~8 |
Ordering Information
| Product | Package Size | Catalog # |
| UniSil® 10-100 C8 | 30 g | 19002-100010-4030 |
| 50 g | 19002-100010-4050 | |
| 100 g | 19002-100010-4100 | |
| 300 g | 19002-100010-4300 | |
| 500 g | 19002-100010-4500 | |
| 1 kg | 19002-100010-3001 | |
| 5 kg | 19002-100010-3005 | |
| 10 kg | 19002-100010-3010 | |
| 50 kg | 19002-100010-3050 | |
| 100 kg | 19002-100010-3100 |