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UniSil 10-100 C8 Reversed-Phase Silica Chromatography Resin

UniSil® 10-100 C8 is a key member of NanoMicro's UniSil® product line. This reversed-phase chromatography resin features a surface-modified UniSil® silica matrix with bonded reversed-phase groups, offering uniform particle size, high mechanical strength, high column efficiency, and high resolution. Its pore structure and chemical bonding are particularly well-suited for the separation and purification of small molecules such as antibiotics, peptides, and natural products.

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UniSil® 10-100 C8 Chemical Structure

UniSil® 10-100 C8 utilizes advanced surface bonding and end-capping technologies, providing excellent chemical stability. After 5 years of storage at room temperature, re-testing of multiple batches shows no significant changes in QC results compared to the initial QC analysis.

Compared to similar products on the market, UniSil®10-100 C8 offers the following unique advantages:

• Monodisperse silica resin with extremely narrow particle size distribution, CV ≤ 5%;

• Precisely controlled pore size and distribution, effective specific surface area, and pore volume for high loading capacity;

• Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application needs;

• Excellent chemical stability, suitable for separation and purification at pH 2-8.


Performance Specifications

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Separation PrincipleReversed-Phase Chromatography
MatrixMonodisperse Silica
Particle Size10 µm
Pore Size100 Å
Particle Size CV≤5%
Pressure Limit<600 bar
Pore Volume~1.00 cm3/g
Specific Surface Area~450 m2/g
Bulk density~0.55 g /mL
Carbon Content~11 %
pH Range2~8


Ordering Information

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Product Package SizeCatalog #
UniSil® 10-100 C830 g19002-100010-4030
50 g19002-100010-4050
100 g19002-100010-4100
300 g19002-100010-4300
500 g19002-100010-4500
1 kg19002-100010-3001
5 kg19002-100010-3005
10 kg19002-100010-3010
50 kg19002-100010-3050
100 kg

19002-100010-3100



Note: NanoMicro also offers preparative columns with inner diameters of 10/21.2/30/50 mm and lengths of 100/150/250 mm. For more specifications or custom options, please contact us.