UniSil 10-120 C8 Ultra Reversed Phase Silica Chromatography Resin
UniSil® 10-120 C18 Ultra is a key member of the NanoMicro UniSil® product line. This reversed-phase resin features surface modification of the UniSil® silica matrix to configure reversed-phase bonded groups (Figure 1), offering uniform particle size, high mechanical strength, high column efficiency, and high resolution. Its pore structure and chemical bonding are particularly well-suited for the separation and purification of small molecules such as antibiotics, peptides, and natural products.
Figure1. Chemical structure of UniSil® 10-120 C18 Ultra
UniSil® 10-120 C18 Ultra employs advanced surface bonding and end-capping technologies, providing excellent chemical stability. After 5 years of storage at room temperature, re-testing of multiple resin lots shows no significant changes in QC results compared to the initial quality control analysis.
Compared to similar products on the market, UniSil® 10-120 C18 Ultra offers the following unique advantages:
Ÿ Monodisperse silica resin with extremely narrow particle size distribution, CV ≤ 5%;
Ÿ Precise control of pore size and distribution, effective specific surface area, and pore volume, enabling high loading capacity;
Ÿ Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application needs;
Ÿ Excellent chemical stability, suitable for separation and purification at pH 2-10.
Performance Specifications
| Separation Principle | Reversed-phase chromatography |
| Matrix | Monodisperse silica |
| Particle Size | 10 µm |
| Pore Size | 120 Å |
| Particle Size CV | ≤5% |
| Pressure Tolerance | ＜600 bar |
| Pore Volume | ~1.10 cm3/g |
| Specific Surface Area | ~360 m2/g |
| Bulk density | ~0.60 g /mL |
| Carbon Content | ≥15% |
| pH Range | 2~10 |
Ordering Information
Product | Package Size | Catalog # |
UniSil® 10-120 C18 Ultra | Standard packaging available in 30g, 50g, 100g, 300g, 500g, 1kg, 5kg, 10kg, 50kg, 100kg | 19101-100012 |