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UniSil 10-120 C4 Reversed-Phase Silica Chromatography Resin

UniSil® 10-120 C4 is a key member of the NanoMicro UniSil® product line. This reversed-phase chromatography resin features reversed-phase bonded groups configured through surface modification of the UniSil® silica matrix, offering uniform particle size, high mechanical strength, high column efficiency, and high resolution. Its pore channels  separation and purification.

UniSil® 10-120 C4 employs advanced surface bonding and end-capping technology, providing excellent chemical stability. After 5 years of storage at room temperature, multiple batches of the resin were retested, and the QC test results showed no significant changes compared to the initial QC analysis results.

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Chemical Structure of UniSil® 10-120 C4


Compared to similar products on the market, UniSil® 10-120 C4 offers the following unique advantages:

  • Monodisperse silica resin with an extremely narrow particle size distribution, CV ≤ 5%;

  • Precise control of pore size and distribution, effective specific surface area, and pore volume, enabling high loading capacity;

  • Unique end-capping technology that effectively modulates residual silanol groups on the silica surface to meet diverse application requirements;

  • Excellent chemical stability, suitable for separation and purification at pH 2-8.

Performance Specifications

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Separation PrincipleReversed-Phase Chromatography
MatrixMonodisperse Silica
Particle Size10 µm
Pore Size120 Å
Particle Size CV≤5%
Pressure Tolerance<600 bar
Pore Volume~1.00 cm3/g
Specific Surface Area~350 m2/g
Bulk Density~0.50 g /mL
Carbon Content6%
pH Range2~8


Ordering Information

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Product Package SizeCatalog #
UniSil® 10-120 C4

30g, 50g, 100g, 300g, 500g, 1kg,

5kg, 10kg, 50kg, 100kg
19003-100012


Note: NanoMicro also offers preparative columns with inner diameters of 10/21.2/30/50 mm and lengths of 100/150/250 mm. For more specifications or custom configurations, please contact us.