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UniSil 10-120 C8 Ultra Reversed-Phase Silica Chromatography Resin

 UniSil® 10-120 C8 Ultra is a key member of NanoMicro's UniSil® product line. This reversed-phase chromatography resin features a uniform particle size, high mechanical strength, high column efficiency, and high resolution, achieved through surface modification of the UniSil® silica matrix with reversed-phase bonded groups. Its pore structure and chemical bonding are particularly well-suited for the separation and purification of small molecules such as antibiotics, peptides, and natural products.

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UniSil® 10-120 C8 Ultra Chemical Structure

UniSil® 10-120 C8 Ultra utilizes advanced surface bonding and end-capping technology, providing excellent chemical stability. After 5 years of storage at room temperature, multiple batches of the resin were retested, and the quality control test results showed no significant changes compared to the initial QC analysis.

Compared to similar products on the market, UniSil® 10-120 C8 Ultra offers the following unique advantages:

  • Monodisperse silica resin with an extremely narrow particle size distribution, CV ≤ 5%;

  • Precisely controlled pore size and distribution, effective specific surface area, and pore volume, resulting in high loading capacity;

  • Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application requirements;

  • Excellent chemical stability, suitable for separation and purification at pH 2-10.


Performance Specifications

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Separation PrincipleReversed-Phase Chromatography
MatrixMonodisperse Silica
Particle Size10 µm
Pore Size120 Å
Particle Size CV≤5%
Pressure Limit<600 bar
Pore Volume~1.0 cm3/g
Specific Surface Area~300 m2/g
Bulk density~0.55 g /mL
Carbon Content≥10%
pH Range2~10


Ordering Information

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Product Package SizeCatalog #
UniSil® 10-120 C8 UltraAvailable in standard packaging of 30g, 50g, 100g, 300g, 500g, 1kg, 5kg, 10kg, 50kg, 100kg19102 - 100012
Note: NanoMicro also offers preparative columns with inner diameters of 10/21.2/30/50 mm and lengths of 100/150/250 mm. For additional specifications or custom configurations, please contact us.