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UniSil 10-120 PFP Reversed-Phase Silica Chromatography Resin

UniSil® 10-120 PFP is a key member of the NanoMicro UniSil®  product line. This reversed-phase chromatography resin features a surface-modified UniSil®  silica matrix with bonded reversed-phase groups, offering uniform particle size, high mechanical strength, high column efficiency, and high resolution. Compared to conventional reversed-phase resins, the fluorinated bonded phase provides stronger polar interactions, delivering excellent selectivity for polar compounds. Additionally, the fluorinated phase exhibits stereoselectivity, enabling the separation of challenging structural isomers.

UniSil® 10-120 PFP utilizes advanced surface bonding and end-capping technology, ensuring excellent chemical stability. After 5 years of storage at room temperature, multiple batches of the resin were retested, and the quality control results showed no significant changes compared to the initial analysis.


Compared to similar products on the market, UniSil® 10-120 PFP offers the following unique advantages:

  • Monodisperse silica resin with an extremely narrow particle size distribution, CV ≤ 5%;

  • Precisely controlled pore size and distribution, effective specific surface area, and pore volume, enabling high loading capacity;

  • Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application requirements;

  • Excellent chemical stability, suitable for separation and purification at pH 2-8.

Performance Specifications

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Separation PrincipleReversed-phase chromatography
MatrixMonodisperse silica
Particle Size10 µm
Pore Size120 Å
Particle Size CV≤5%
Pressure Tolerance<600 bar
Pore Volume~1.00 cm3/g
Specific Surface Area~300 m2/g
Bulk density~0.55 g /mL
Carbon Content≥9 %
pH Range2~8


Ordering Information

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Product Package SizeCatalog #
UniSil® 10-120 PFP30 g19204-100012-4030
50 g19204-100012-4050
100 g19204-100012-4100
300 g19204-100012-4300
500 g19204-100012-4500
1 kg19204-100012-3001
5 kg19204-100012-3005
10 kg19204-100012-3010
50 kg19204-100012-3050
100 kg19204-100012-3100


Note: NanoMicro also offers preparative columns with inner diameters of 10/21.2/30/50 mm and lengths of 100/150/250 mm. For additional specifications or custom configurations, please contact us.