UniSil 10-300 C18 Reversed-Phase Silica Chromatography Resin

UniSil^® 10-300 C18 is a key member of NanoMicro's UniSil® product line. This reversed-phase chromatography resin features reversed-phase bonded groups configured through surface modification of the UniSil® silica matrix (Figure 1), offering uniform particle size, high mechanical strength, high column efficiency, and high resolution. Its pore structure and chemical bonding are particularly well-suited for the separation and purification of small molecules such as antibiotics, peptides, and natural products.

UniSil^® 10-300 C18 utilizes advanced surface bonding and end-capping technology, providing excellent chemical stability. After 5 years of storage at room temperature, multiple batches of the resin were retested, and the quality control results showed no significant changes compared to the initial quality control analysis.

UniSil^® 10-300 C18 Chemical Structure

Compared to similar products on the market, UniSil^® 10-300 C18 offers the following unique advantages:

• Monodisperse silica resin with an extremely narrow particle size distribution, CV ≤ 5%;

• Precisely controlled pore size and distribution, effective specific surface area, and pore volume, enabling high loading capacity;

• Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application requirements;

• Excellent chemical stability, suitable for separation and purification at pH 2-8.