UniSil 10-300 C4 Reversed-Phase Silica Chromatography Resin
UniSil® 10-300 C4 is a key member of the NanoMicro UniSil® product line. This reversed-phase chromatography resin features reversed-phase bonded groups configured through surface modification of the UniSil® silica matrix (Figure 1), offering uniform particle size, high mechanical strength, high column efficiency, and high resolution. Its pores are designed for separation and purification.
UniSil® 10-300 C4 utilizes advanced surface bonding and end-capping technology, providing excellent chemical stability. After 5 years of storage at room temperature, multiple batches of the resin were retested, and the QC test results showed no significant changes compared to the initial QC analysis.
Chemical Structure of UniSil® 10-300 C4
Compared to similar products on the market, UniSil® 10-300 C4 offers the following unique advantages:
Monodisperse silica resin with extremely narrow particle size distribution, CV ≤ 5%;
Precisely controlled pore size and distribution, effective specific surface area, and pore volume, enabling high loading capacity;
Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application requirements;
Excellent chemical stability, suitable for separation and purification at pH 2-8.
Performance Specifications
| Separation Principle | Reversed-Phase Chromatography |
| Matrix | Monodisperse Silica |
| Particle Size | 10 µm |
| Pore Size | 300 Å |
| Particle Size CV | ≤5% |
| Pressure Tolerance | <600 bar |
| Pore Volume | ~1.00 cm3/g |
| Specific Surface Area | ~100 m2/g |
| Bulk density | ~0.40 g/mL |
| Carbon Content | 3% |
| pH Range | 2~8 |
Ordering Information
| Product | Package Size | Catalog # |
| UniSil® 10-300 C4 | 30g, 50g, 100g, 300g, 500g, 1kg, 5kg, 10kg, 50kg, 100kg | 19003-100030 |