UniSil 10-300 C8 Reversed-Phase Silica Chromatography Resin

UniSil^® 10-300 C8 is a key member of the NanoMicro UniSil^®  product line. This reversed-phase chromatography resin features reversed-phase bonded groups configured through surface modification of the UniSil^®  silica matrix (Figure 1), offering uniform particle size, high mechanical strength, high column efficiency, and high resolution. Its pore structure and chemical bonding are particularly well-suited for the separation and purification of small molecules such as antibiotics, peptides, and natural products.

UniSil^® 10-300 C8 employs advanced surface bonding and end-capping technology, providing excellent chemical stability. After 5 years of storage at room temperature, multiple batches of the resin were retested, and the quality control results showed no significant changes compared to the initial QC analysis.

Chemical Structure of UniSil^®10-300 C8

Compared to similar products on the market, UniSil^®10-300 C8 offers the following unique advantages:

• Monodisperse silica resin with an extremely narrow particle size distribution, CV ≤ 5%;

• Precisely controlled pore size and distribution, effective specific surface area, and pore volume, resulting in high loading capacity;

• Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application requirements;

• Excellent chemical stability, suitable for separation and purification at pH 2-8.