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UniSil 30-300 C4 Reversed-Phase Silica Chromatography Resin

UniSil® 30-300 C4 is a key member of the NanoMicro UniSil® product line. This reversed-phase chromatography resin features a UniSil® silica matrix with surface-modified reversed-phase bonded groups (Figure 2), offering uniform particle size, high mechanical strength, high column efficiency, and high resolution. Its pore structure is designed for  separation and purification.

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Figure 1. Chemical structure of UniSil® 30-300 C4

UniSil® 30-300 C4 utilizes advanced surface bonding and end-capping technology, providing excellent chemical stability. After 5 years of storage at room temperature, re-testing of multiple batches of the resin shows no significant changes in quality control results compared to the initial analysis.

Compared to similar products on the market, UniSil® 30-300 C4 offers the following unique advantages:

• Monodisperse silica resin with extremely narrow particle size distribution, CV ≤ 5%;

• Precisely controlled pore size and distribution, effective specific surface area, and pore volume for high loading capacity;

• Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application needs;

• Excellent chemical stability, suitable for separation and purification at pH 2~8.


Performance Specifications

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Separation PrincipleReversed-Phase Chromatography
MatrixMonodisperse Silica
Particle Size30 µm
Pore Size300 Å
Particle Size CV≤5%
Pressure Tolerance<600 bar
Pore Volume~1.00 cm3/g
Specific Surface Area~110 m2/g
Bulk density~0.50 g /mL
Carbon Content3%
pH Range2~8



Ordering Information

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Product Package SizeCatalog #
UniSil® 30-300 C430g, 50g, 100g, 300g, 500g, 1 kg, 5 kg, 10 kg, 50 kg, 100 kg19003-300030


Note: NanoMicro also offers preparative columns with inner diameters of 10/21.2/30/50 mm and lengths of 100/150/250 mm. For additional specifications or custom configurations, please contact us.