UniSil 30-300 C4 Reversed-Phase Silica Chromatography Resin
UniSil® 30-300 C4 is a key member of the NanoMicro UniSil® product line. This reversed-phase chromatography resin features a UniSil® silica matrix with surface-modified reversed-phase bonded groups (Figure 2), offering uniform particle size, high mechanical strength, high column efficiency, and high resolution. Its pore structure is designed for separation and purification.

Figure 1. Chemical structure of UniSil® 30-300 C4
UniSil® 30-300 C4 utilizes advanced surface bonding and end-capping technology, providing excellent chemical stability. After 5 years of storage at room temperature, re-testing of multiple batches of the resin shows no significant changes in quality control results compared to the initial analysis.
Compared to similar products on the market, UniSil® 30-300 C4 offers the following unique advantages:
• Monodisperse silica resin with extremely narrow particle size distribution, CV ≤ 5%;
• Precisely controlled pore size and distribution, effective specific surface area, and pore volume for high loading capacity;
• Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application needs;
• Excellent chemical stability, suitable for separation and purification at pH 2~8.
Performance Specifications
| Separation Principle | Reversed-Phase Chromatography |
| Matrix | Monodisperse Silica |
| Particle Size | 30 µm |
| Pore Size | 300 Å |
| Particle Size CV | ≤5% |
| Pressure Tolerance | <600 bar |
| Pore Volume | ~1.00 cm3/g |
| Specific Surface Area | ~110 m2/g |
| Bulk density | ~0.50 g /mL |
| Carbon Content | 3% |
| pH Range | 2~8 |
Ordering Information
| Product | Package Size | Catalog # |
| UniSil® 30-300 C4 | 30g, 50g, 100g, 300g, 500g, 1 kg, 5 kg, 10 kg, 50 kg, 100 kg | 19003-300030 |