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UniSil Revo 10-120 C18 Reversed Phase Silica Chromatography Resin

UniSil® Revo 10-120 C18 is a key member of NanoMicro's UniSil® product line. Featuring revolutionary micropore control technology, the pores are interconnected with thicker pore walls, resulting in superior mechanical strength, selectivity, and pH tolerance. This reversed-phase chromatography resin is configured with reversed-phase bonded groups through surface modification of the UniSil® silica matrix (Figure 1). Its pore structure and chemical bonding are particularly well-suited for the separation and purification of small molecules such as GLP-1, insulin, peptides, and oligonucleotides.

UniSil® Revo 10-120 C18 employs advanced surface bonding and end-capping technologies, providing excellent chemical stability.

Chemical Structure of UniSil® Revo 10-120 C18


Compared to similar products on the market, UniSil® Revo 10-120 C18 offers the following unique advantages:

  • Monodisperse silica resin with an extremely narrow particle size distribution, CV ≤ 5%;

  • Revolutionary micropore control technology enables interconnected pores, increasing effective specific surface area and pore volume, resulting in high loading capacity and high resolution;

  • Unique end-capping technology effectively modulates residual silanol groups on the silica surface to meet diverse application requirements;

  • Excellent chemical stability, suitable for separation and purification at pH 2-9.

  • Compatible with 100% aqueous mobile phases.

Performance Specifications

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Separation PrincipleReversed-phase chromatography
MatrixMonodisperse silica
Particle Size10 µm
Pore Size120 Å
Particle Size CV≤5%
Pressure Limit<600 bar
Pore Volume~1.10 cm3/g
Specific Surface Area~320 m2/g
Bulk density~0.55 g /mL
Carbon Content12%
pH Range2~9


Ordering Information

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Product Package SizeCatalog #
UniSil® Revo 10-120 C18

Available in standard packaging of 30g, 50g, 100g, 300g, 500g, 1kg,

5kg, 10kg, 50kg, 100kg
19701-100012


Note: NanoMicro also offers preparative columns with inner diameters of 10/21.2/30/50 mm and lengths of 100/150/250 mm. For additional specifications or custom configurations, please contact us.