UniHybrid 8-120 C8 Hybrid Silica Chromatography Resin
The UniHybrid® series is manufactured from high-purity, monodisperse, porous silica microspheres produced using NanoMicro's proprietary technology. A dense surface hybridization is applied to the particle surface and pore structure, introducing an organic-inorganic hybrid layer containing methylene bridge structures onto the silica surface, followed by bonding and end-capping. This unique surface hybridization technology significantly enhances the chemical stability of the resin, providing acid and base pH tolerance comparable to polymer-based resins. As a result, it combines the mechanical strength of high-purity silica resins with the chemical stability of polymer resins, along with the superior performance derived from both in chromatographic purification. Additionally, the surface chemistry modification alters the silanol density and increases the carbon content, imparting unique separation selectivity to the hybrid silica.

Compared to similar products on the market, UniHybrid® 8-120 C8 offers the following unique advantages:
Monodisperse silica resin with an extremely narrow particle size distribution, CV ≤ 5%;
Precisely controlled pore size and distribution, effective surface area, and pore volume for high loading capacity;
Uniform particle size, surface modification, and pore design deliver high column efficiency and excellent separation and purification performance;
Excellent chemical stability, suitable for purification across pH 1-11.
Performance Specifications
| Separation Principle | Reversed Phase Chromatography |
| Matrix | Monodisperse Silica |
| Particle Size | 8 µm |
| Pore Size | 120 Å |
| Particle Size CV | ≤5% |
| Pressure Limit | <600 bar |
| Pore Volume | ~1.00cm3/g |
| Specific Surface Area | ~310 m2/g |
| Bulk density | ~0.60 g /mL |
| Carbon Content | ~13% |
| pH Range | 1~11 |
Ordering Information
| Product | Package Size | Catalog # |
| UniHybrid® 8-120 C8 | 30 g | 19502-080012-4030 |
| 50 g | 19502-080012-4050 | |
| 100 g | 19502-080012-4100 | |
| 300 g | 19502-080012-4300 | |
| 500 g | 19502-080012-4500 | |
| 1 kg | 19502-080012-3001 | |
| 5 kg | 19502-080012-3005 | |
| 10 kg | 19502-080012-3010 | |
| 50 kg | 19502-080012-3050 | |
| 100 kg | 19502-080012-3100 |