OSM-LabST 300Pro
The OSM-LabST 300Pro solvent-resistant concentration and impurity removal workstation is an upgraded integrated system designed for process development and small-to-medium scale testing. This model delivers comprehensive improvements in performance and user experience within a compact footprint. With a minimum circulation volume of only 300 mL and an adjustable processing throughput of 1L–5L per hour, it seamlessly bridges laboratory-scale data generation and reliable pilot-scale validation prior to process scale-up. The system features an integrated intelligent control system and a user-friendly interface, significantly simplifying parameter setup and process monitoring—even non-specialists can quickly master its operation. Its modular, compact design optimizes both equipment performance and laboratory space utilization, making it ideal for deployment in limited R&D or pilot facilities. The system is fully compatible with a wide range of solvent-resistant membrane cassettes, covering
Product Description
Applications: Covering Multiple Process Development Workflows
1. Small molecule API concentration and impurity removal
2. Biologics (protein/peptide) desalting and buffer exchange
3. Natural product extract concentration and solvent exchange
4. Fine chemical intermediate purification and solvent recovery
5. CRO/CMO multi-project process validation and customized experiments
Core Value: 3 Key Advantages Addressing R&D Pain Points
POC Proof of Concept · Cost-Effective | Full-Chain Compatibility · No Scale-Up Barriers | Precise Data Acquisition · Reproducible Process |
Addressing the challenges of limited sample volumes and tight timelines in early-stage R&D/CRO, we provide efficient feasibility validation for micro-scale samples, covering core processes such as API concentration, solvent exchange, and desalting/salt exchange to avoid ineffective investment. | Membrane materials, consumables, and components are identical to those used in commercial scale-up production, enabling direct acquisition of authoritative “material compatibility + extractables/leachables” data, thoroughly resolving the industry pain point of “feasible in the lab, infeasible in production.” | Real-time monitoring of critical parameters such as membrane flux and retention rate, providing comprehensive evaluation of membrane processing capacity, tolerance, fouling resistance, and cleaning/recovery performance, delivering reproducible and robust data for process finalization. |
Flexible Configuration: Tailored to Diverse R&D Needs
Membrane Cassette Type Matching
Cassette Model | Applicable Solvent Systems | Core Applications | Recommended Priority |
PHD | Alcohol/water, low-to-medium concentration acetonitrile-water | Routine API concentration, desalting, buffer exchange | First choice for high-throughput desalting |
PHF | Alcohol/water, low-to-medium concentration acetonitrile-water | Routine API concentration, desalting, buffer exchange | First choice for API concentration and buffer exchange |
PHR | Alcohol/water, low-to-medium concentration acetonitrile-water | Polar solvent impurity removal and purification | Polar solvent purification |
DHR | High-concentration acetonitrile-water, DMF/acetone | API concentration and solvent impurity removal in strongly polar solvent systems | Dedicated for high-concentration strongly polar solvents |
NHR | Alkanes, ethyl acetate, halogenated alkanes, aromatic hydrocarbons | API concentration and solvent impurity removal in non-polar solvent systems | Dedicated for non-polar solvents |
* Note: 1. Membrane cassette area options: 0.005/0.05/0.1 m²
Robust Specifications: Stable and Reliable for Complex Environments
• Pressure Control:Up to 40 bar, precise adjustment
• Temperature Compatibility:Operating temperature not exceeding 40 °C
• pH Tolerance:Long-term 3-10, short-term 2-12
• Material Compatibility:SUS316L medical-grade stainless steel + solvent-resistant primary/auxiliary materials
• Ease of Operation:Integrated design, easy-to-clean tubing
Ordering Information
