OSM-LabST 050Pro
The OSM-LabST 050Pro solvent-resistant concentration and impurity removal workstation is designed for R&D and analytical applications where sample volumes are limited and process development costs are a key concern. Its compact architecture and precise fluid control system achieve a minimum circulation volume of just 50 mL, effectively addressing the challenges of testing微量, precious samples during process development. The system supports a processing throughput of 0.1L–0.5L per hour, enabling efficient solvent concentration, target separation, and impurity removal with minimal material consumption, significantly reducing early-stage R&D material and time costs. Fully compatible with solvent-resistant nanofiltration membrane cassettes, it covers a wide range of organic solvent systems from polar to non-polar, providing users with a small-scale, high-precision, and highly reproducible process validation platform. It is a reliable tool bridging laboratory research and process scale-up.
Product Description
Applications: Covering Multiple Process Development Workflows
1. Small molecule API concentration and impurity removal
2. Biologics (protein/peptide) desalting and buffer exchange
3. Natural product extract concentration and solvent exchange
4. Fine chemical intermediate purification and solvent recovery
5. CRO/CMO multi-project process validation and customized experiments
Core Value: 3 Key Advantages Addressing R&D Pain Points
POC Proof of Concept – Low Cost, High Efficiency | Full-Chain Compatibility – No Scale-Up Barriers | Precise Data Acquisition – Reproducible Processes |
Addressing the limited sample volumes and tight timelines typical of early-stage R&D and CRO projects, we provide efficient feasibility validation solutions for micro-scale samples, covering core processes such as API concentration, solvent exchange, and desalting/salt exchange to avoid ineffective investment. | Membrane materials, consumables, and components are consistent with commercial-scale production, providing authoritative material compatibility and extractables/leachables data directly, effectively resolving the industry pain point of "feasible in the lab, infeasible in production." | Real-time monitoring of critical parameters such as membrane flux and rejection rate provides a comprehensive evaluation of membrane processing capacity, tolerance, fouling resistance, and cleaning/recovery performance, delivering reproducible, robust data for process definition. |
Flexible Configuration: Tailored to Diverse R&D Needs
Membrane Cassette Model | Applicable Solvent Systems | Core Applications | Recommended Priority |
PHD | Alcohol/water, low-to-medium concentration acetonitrile-water | Routine API concentration, desalting, buffer exchange | First choice for high-throughput desalting |
PHF | Alcohol/water, low-to-medium concentration acetonitrile-water | Routine API concentration, desalting, buffer exchange | First choice for API concentration and buffer exchange |
PHR | Alcohol/water, low-to-medium concentration acetonitrile-water | Polar solvent impurity removal and purification | Polar solvent purification |
DHR | High-concentration acetonitrile-water, DMF/acetone | API concentration and solvent impurity removal in strongly polar solvent systems | Dedicated for high-concentration strongly polar systems |
NHR | Alkanes, ethyl acetate, halogenated alkanes, aromatic hydrocarbons | API concentration and solvent impurity removal in non-polar solvent systems | Dedicated for non-polar systems |
* Note: 1. Membrane cassette area options: 0.005/0.05/0.1 m²
Robust Specifications: Stable and Reliable for Complex Environments
• Pressure Control:Up to 40 bar with precise adjustment
• Temperature Compatibility:Operating temperature up to 40 °C
• pH Tolerance:Long-term 3-10, short-term 2-12
• Material Compatibility:SUS316L medical-grade stainless steel with solvent-resistant primary and auxiliary materials
• Ease of Operation:Integrated design with easy-to-clean tubing
Ordering Information
