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Protein L Affinity Chromatography Pre-packed Column

Protein L specifically binds to antibody light chains (κ light chains) independent of the Fc region, enabling purification of antibodies, single-chain antibodies, and Fab fragments that do not bind to Protein A/G.

  • Protein L 亲和层析预装柱.png

Product Description

NMab Prot L features a highly cross-linked agarose matrix with a proprietary recombinant ligand that specifically binds to antibody κ light chains, enabling purification of Fab, scFv, and other antibody fragments that are difficult to capture with Protein A/G. The epoxy covalent coupling ensures minimal ligand leakage, delivering high dynamic binding capacity, excellent product purity, and superior yield. As a fully domestic, self-developed product across the entire industrial chain, it serves as a direct replacement for imported alternatives.

Complete compliance documentation: resin extractables, heavy metals, and microbial testing reports are available to support biologics regulatory filings.

Performance Specifications

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Protein L亲和层析预装柱_Protein L 亲和层析介质-技术参数表 EN.png

Ordering Information

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Prepacked column specificationsCat. No.Prepacked column specificationsCat. No.
NmTRAP 1mL, NMab ProtL77221-17050-070100NmVALID 35/100, NMab ProtL35101-17050-070100
NmTRAP 5mL, NMab ProtL16255-17050-070100NmVALID 35/200, NMab ProtL35201-17050-070100
NmSCREEN 4.7mL, NMab ProtL77105-17050-070100NmVALID 50/100, NMab ProtL50106-17050-070100
NmPREP 16/100, NMab ProtL16103-17050-070100NmVALID 50/200, NMab ProtL50206-17050-070100
NmPREP 26/100, NMab ProtL26153-17050-070100NmPILOT 70/100, NMab ProtL70105-17050-070100
NmVALID 8/100, NMab ProtL08101-17050-070100NmPILOT 70/150, NMab ProtL70155-17050-070100
NmVALID 8/200, NMab ProtL08201-17050-070100NmPILOT 100/100, NMab ProtL10105-17050-070100
NmVALID 11/100, NMab ProtL11101-17050-070100NmPILOT 100/200, NMab ProtL10205-17050-070100
NmVALID 11/200, NMab ProtL11201-17050-070100NmPILOT 140/100, NMab ProtL14105-17050-070100
NmVALID 16/100, NMab ProtL16106-17050-070100NmPILOT 140/200, NMab ProtL14205-17050-070100
NmVALID 16/200, NMab ProtL16206-17050-070100NmPILOT 200/100, NMab ProtL20105-17050-070100
NmVALID 26/100, NMab ProtL26106-17050-070100NmPILOT 200/200, NMab ProtL20205-17050-070100
NmVALID 26/200, NMab ProtL26206-17050-070100

**Due to space limitations, only part of the products are listed here. For more prepacked column specifications, please contact us.