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NW Rose Series Gel Filtration Pre-packed Columns
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NW Super Series Gel Filtration Pre-packed Columns
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NW Dex Series Gel Filtration Pre-packed Columns
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NW Rose Plus HP Series HIC Pre-packed Columns
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UniHR Butyl HIC Pre-packed Column
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UniHR Phenyl HIC Pre-packed Column
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NW Rose Viral Multimodal Pre-packed Column
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Protein A Affinity Chromatography Pre-packed Columns
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Protein G Affinity Chromatography Pre-packed Columns
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Protein L Affinity Chromatography Pre-packed Column
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IMAC Affinity Chromatography Pre-packed Columns
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Anti-A Anti-B Affinity Chromatography Pre-packed Column
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Low-Pressure Pilot-Scale Columns - NmPILOT Plus Series
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Medium-Pressure Pilot-Scale Prep Columns - NmPILOT Series
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PP Column - NmPREP Series
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PP Column - NmSCREEN Series
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PP Column - NmTRAP Series
Anti-A Anti-B Affinity Chromatography Pre-packed Column
Immunoglobulin (Ig) derived from plasma contains trace amounts of anti-A and anti-B agglutinins, which can increase the risk of hemolysis in patients and may sometimes lead to fatal complications. The Chinese Pharmacopoeia (2020 Edition) requires anti-A and anti-B levels to be ≤1:64. To meet this requirement, anti-A anti-B immunoaffinity chromatography can be performed after two-step chromatography to effectively remove anti-A and anti-B antibodies from Ig, significantly improving purity and safety without compromising process economics.
Product Description
UniMab Anti-A & UniMab Anti-B are prepared by coupling polysaccharide antigens A/B onto monodisperse poly(methyl methacrylate) (PMMA) microspheres. They feature high binding capacity, low ligand leakage, and high selectivity, along with enhanced hydrophilicity, reduced non-specific adsorption, higher recovery, and longer service life. Specifically designed for efficient removal of anti-A and anti-B agglutinin antibodies from plasma-derived Ig.
Performance Specifications
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Ordering Information
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| Prepacked column specifications | Cat. No. | Prepacked column specifications | Cat. No. |
| NmTRAP 1mL, UniMab Anti-A | 77221-17060-000001 | NmTRAP 1mL, UniMab Anti-B | 77221-17060-000002 |
| NmTRAP 5mL, UniMab Anti-A | 16255-17060-000001 | NmTRAP 5mL, UniMab Anti-B | 16255-17060-000002 |
| NmSCREEN 4.7mL, UniMab Anti-A | 77105-17060-000001 | NmSCREEN 4.7mL, UniMab Anti-B | 77105-17060-000002 |
| NmPREP 16/100, UniMab Anti-A | 16103-17060-000001 | NmPREP 16/100, UniMab Anti-B | 16103-17060-000002 |
| NmPREP 26/100, UniMab Anti-A | 26153-17060-000001 | NmPREP 26/100, UniMab Anti-B | 26153-17060-000002 |
| NmVALID 8/100, UniMab Anti-A | 08101-17060-000001 | NmVALID 8/100, UniMab Anti-B | 08101-17060-000002 |
| NmVALID 8/200, UniMab Anti-A | 08201-17060-000001 | NmVALID 8/200, UniMab Anti-B | 08201-17060-000002 |
| NmVALID 11/100, UniMab Anti-A | 11101-17060-000001 | NmVALID 11/100, UniMab Anti-B | 11101-17060-000002 |
| NmVALID 11/200, UniMab Anti-A | 11201-17060-000001 | NmVALID 11/200, UniMab Anti-B | 11201-17060-000002 |
| NmVALID 16/100, UniMab Anti-A | 16106-17060-000001 | NmVALID 16/100, UniMab Anti-B | 16106-17060-000002 |
| NmVALID 16/200, UniMab Anti-A | 16206-17060-000001 | NmVALID 16/200, UniMab Anti-B | 16206-17060-000002 |
| NmVALID 26/100, UniMab Anti-A | 26106-17060-000001 | NmVALID 26/100, UniMab Anti-B | 26106-17060-000002 |
| NmVALID 26/200, UniMab Anti-A | 26206-17060-000001 | NmVALID 26/200, UniMab Anti-B | 26206-17060-000002 |
| NmVALID 35/100, UniMab Anti-A | 35101-17060-000001 | NmVALID 35/100, UniMab Anti-B | 35101-17060-000002 |
| NmVALID 35/200, UniMab Anti-A | 35201-17060-000001 | NmVALID 35/200, UniMab Anti-B | 35201-17060-000002 |
| NmVALID 50/100, UniMab Anti-A | 50106-17060-000001 | NmVALID 50/100, UniMab Anti-B | 50106-17060-000002 |
| NmVALID 50/200, UniMab Anti-A | 50206-17060-000001 | NmVALID 50/200, UniMab Anti-B | 50206-17060-000002 |
| NmPILOT 70/100，UniMab Anti-A | 70105-17060-000001 | NmPILOT 70/100，UniMab Anti-B | 70105-17060-000002 |
| NmPILOT 70/200，UniMab Anti-A | 70205-17060-000001 | NmPILOT 70/200，UniMab Anti-B | 70205-17060-000002 |
| NmPILOT 100/100，UniMab Anti-A | 10105-17060-000001 | NmPILOT 100/100，UniMab Anti-B | 10105-17060-000002 |
| NmPILOT 100/200，UniMab Anti-A | 10205-17060-000001 | NmPILOT 100/200，UniMab Anti-B | 10205-17060-000002 |
| NmPILOT 140/100，UniMab Anti-A | 14105-17060-000001 | NmPILOT 140/100，UniMab Anti-B | 14105-17060-000002 |
| NmPILOT 140/200，UniMab Anti-A | 14205-17060-000001 | NmPILOT 140/200，UniMab Anti-B | 14205-17060-000002 |
| NmPILOT 200/100，UniMab Anti-A | 20105-17060-000001 | NmPILOT 200/100，UniMab Anti-B | 20105-17060-000002 |
| NmPILOT 200/200，UniMab Anti-A | 20205-17060-000001 | NmPILOT 200/200，UniMab Anti-B | 20205-17060-000002 |